GLP-Designated Items for Pharmaceuticals (Nonclinical Test Facility)

General Toxicity Tests

  • Single-Dose Toxicity Test (rodents, non-rodents)
  • Repeated-Dose Toxicity Test (rodents, non-rodents)

In Vitro / In Vivo Genotoxicity Tests

  • Reverse Mutation Test
  • Chromosomal Aberration Test
  • Micronucleus Test

Local Toxicity Tests

  • Skin Irritation Test
  • Ocular Mucosa Irritation Test

GLP-Designated Items for Medical Devices (Nonclinical Test Facility)

In Vitro / In Vivo Genotoxicity Tests

  • Reverse Mutation Test
  • Chromosomal Aberration Test
  • Micronucleus Test

Hemocompatibility Test

  • In Vitro Test (Hemolysis Test)

Cytotoxicity Tests

  • Extract Test
  • Test by Indirect Contact

Implantation Tests

  • Subcutaneous Tissue Implantation Test
  • Intramuscular Implantation Test
  • Bone Tissue Implantation Test

Irritation and Skin Sensitization Tests

  • Intracutaneous Reactivity Test
  • Oral Mucosa Irritation Test
  • Guinea Pig Test for Skin Sensitization Detection

Systemic Toxicity Tests

  • Acute Systemic Toxicity Test
  • Repeated-Exposure Systemic Toxicity Test (subacute/subchronic)
  • Pyrogenicity Test (material-mediated)

Inspection-Target Item Categories of the Medical Device Testing & Inspection Institution

Items in the following 11 item categories.

The 11 inspection-target item categories of the Medical Device Testing & Inspection Institution - item name and exclusions or limitations
Item Category Exclusions or Limitations
Procedural Instruments & DevicesExcluding cardiovascular instruments and urological instruments
Biophysiological Measurement DevicesLimited to medical probes and measuring & guiding instruments
Medical Treatment Instruments & DevicesExcluding medical washers, dental engines, and medical inhalers
Syringes & NeedlesExcluding acupuncture or moxibustion instruments
Dental Treatment Instruments & DevicesLimited to dental broaches, dental probes, dental dams, and impression-taking & occlusion instruments
Implantable Medical Supplies-
Human Tissue or Functional Substitutes-
External Medical SuppliesExcluding splints
Contraceptive Devices-
Dental Alloys-
Dental Treatment Materials-

Efficacy Evaluation Tests

  • Anticancer Drug Efficacy Evaluation
  • Bone Regeneration Efficacy Evaluation
  • Liver Cirrhosis Regeneration Efficacy Evaluation
  • Corneal Regeneration Efficacy Evaluation
  • Renal Failure Regeneration Efficacy Evaluation
  • Other Efficacy Evaluations Using Animal Models (available through consultation)

Other

  • Internal Research Support (experiment support and specimen analysis services)
  • Consultation on the Development and Approval Process of Pharmaceuticals and Medical Devices