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마취 진통제

실험동물 종별 마취제·진통제

서울대학교병원 전임상실험부의 실험동물 종별 마취제와 진통제 정보를 표와 같이 정리하였습니다.

Anesthesia Drugs (마취제)

실험동물 종별 마취제 - 약물·용량·투여 경로·Induction/Maintenance
Species	Drugs	Dose (mg/kg)	Route	Induction · Maintenance
Mouse	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	(5~16) + (100~200) (5~16) + (5~20) 1~3%	IP Inhalation	Injection or inhalation
Rat	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	(5~13) + (40~87) (5~16) + (5~20) 1~3%	IP, IM Inhalation	Injection or inhalation
Hamster	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	(5~10) + (50~200) (5~10) + (20~30) 2~5%	IP, IM Inhalation	Injection or inhalation
Guinea Pigs	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	(5~13) + (40~87) (5~16) + (5~20) 1~3%	IP, IM Inhalation	Injection or inhalation
Rabbit	Xylazine + Ketamine Zoletil + Xylazine Isoflurane	(5~10) + (35~50) (15) + (5) 1~3%	IV IM Inhalation	Injection Inhalation
Dog	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	(1~2) + 5 2 + 5 1~3%	IM, IV IM, IV Inhalation	Injection Inhalation
Pig	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	(1~2) + (10~20) 2 + 5 1~3%	IM IM Inhalation	Injection Inhalation
NHPs (Macaque)	Xylazine + Ketamine Xylazine + Zoletil Isoflurane	0.5 + (5~10) 0.5 + 5 1~2%	IM IM Inhalation	Injection Inhalation
NHPs (Marmoset)	Xylazine + Ketamine Zoletil Isoflurane	3 + (10~20) 10 1~2%	IM IM Inhalation	Injection Inhalation

Analgesics (진통제)

실험동물 종을 선택하시면 해당 종의 진통제 권장 용량 및 적용 정보를 확인하실 수 있습니다.

Mouse, Rat

Mouse·Rat 진통제 정보
Analgesics	Dosage	Duration	Comment
Acetylsalicylic acid	100~150 mg/kg, PO	4 hours	NSAIDs
Acetaminophen	200 mg/kg, PO	-	NSAIDs
Ketoprofen	5 mg/kg, SC, IM	24 hours	NSAIDs
Meloxicam	1~2 mg/kg, PO, SC	24 hours	NSAIDs
Buprenorphine	0.05~2.5 mg/kg, SC, IP	6~12 hours	Opioid
Butorphanol	0.2~2 mg/kg, SC, IP	2~4 hours	Opioid
Tramadol	5~20 mg/kg, SC	12~24 hours	Opioid

Hamster

Hamster 진통제 정보
Analgesics	Dosage	Duration	Comment
Ketoprofen	5 mg/kg, SC, IP	-	NSAIDs
Meloxicam	1~2 mg/kg, PO, SC, IM, PI	-	NSAIDs
Buprenorphine	0.1~0.5 mg/kg, SC	6~12 hours	Opioid
Butorphanol	1~5 mg/kg, SC, IP	-	Opioid

Guinea Pigs

Guinea Pigs 진통제 정보
Analgesics	Dosage	Duration	Comment
Ketoprofen	1 mg/kg, SC, IM	24 hours	NSAIDs
Meloxicam	0.1~0.3 mg/kg, PO, SC	24 hours	NSAIDs
Buprenorphine	0.01~0.05 mg/kg, SC, IP	6~12 hours	Opioid

Rabbit

Rabbit 진통제 정보
Analgesics	Dosage	Duration	Comment
Acetylsalicylic acid	100 mg/kg, PO	8~24 hours	NSAIDs
Acetaminophen	200~500 mg/kg, PO	-	NSAIDs
Ketoprofen	3 mg/kg, SC, IM	24 hours	NSAIDs
Meloxicam	0.2 mg/kg, SC 0.3 mg/kg, PO	24 hours	NSAIDs
Buprenorphine	0.01~0.05 mg/kg, SC, IM, IV	6~12 hours	Opioid
Butorphanol	0.1~1 mg/kg, SC, IM, IV	4~6 hours	Opioid
Tramadol	5 mg/kg, SC, IV	8 hours	Opioid

Dog

Dog 진통제 정보
Analgesics	Dosage	Duration	Comment
Acetylsalicylic acid	10~20 mg/kg, PO	12 hours	NSAIDs
Ketorolac	15~30 mg/kg, IM, IV	12 hours	NSAIDs
Ketoprofen	2 mg/kg, IV, SC	24 hours	NSAIDs
Meloxicam	0.2 mg/kg, IV, SC, PO	24 hours	NSAIDs
Buprenorphine	0.01~0.02 mg/kg, SC, IM	6~8 hours	Opioid
Butorphanol	0.1~0.5 mg/kg, IM, IV	4 hours	Opioid
Fentanyl	0.02~0.04 mg/kg, SC, IM, IV	1/2 hours	Opioid

Pig

Pig 진통제 정보
Analgesics	Dosage	Duration	Comment
Acetylsalicylic acid	10~20 mg/kg, PO	4 hours	NSAIDs
Ketorolac	1 mg/kg, IM, IV	12 hours	NSAIDs
Ketoprofen	1~3 mg/kg, IV, SC, PO	12 hours	NSAIDs
Meloxicam	0.4 mg/kg, IV, SC	24 hours	NSAIDs
Buprenorphine	0.005~0.1 mg/kg, SC, IM, IV	8~12 hours	Opioid
Butorphanol	0.1~0.3 mg/kg, SC, IM, IV	8~12 hours	Opioid
Tramadol	2~4 mg/kg, IM	12~24 hours	Opioid

NHPs (Macaque)

NHPs (Macaque) 진통제 정보
Analgesics	Dosage	Duration	Comment
Acetylsalicylic acid	20 mg/kg, PO	6~8 hours	NSAIDs
Acetaminophen	10 mg/kg, PO	6~8 hours	NSAIDs
Ketoprofen	5 mg/kg, IM	8 hours	NSAIDs
Meloxicam	0.1~0.3 mg/kg, SC	24 hours	NSAIDs
Buprenorphine	0.005~0.01 mg/kg, IM	8 hours	Opioid
Butorphanol	0.1~0.5 mg/kg, IM, IV	4 hours	Opioid
Fentanyl	0.02~0.04 mg/kg, SC, IM, IV	1/2 hours	Opioid

NHPs (Marmoset)

NHPs (Marmoset) 진통제 정보
Analgesics	Dosage	Duration	Comment
Meloxicam	0.2 mg/kg, SC	24 hours	NSAIDs
Buprenorphine	0.015 mg/kg, SC, IM	6~8 hours	Opioid